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REVIA should be considered as only one of many factors determining the success of treatment of alcoholismFactors associated with a good outcome in the clinical trials with REVIA were the typeintensityand duration of treatmentappropriate management of comorbid conditionsuse of community-based support groupsand good medication complianceTo achieve the best possible treatment outcomeappropriate compliance-enhancing techniques should be implemented for all components of the treatment programespecially medication compliance.

Naltrexone is used along with counseling and social support to help people who have stopped drinking alcohol and using street drugs continue to avoid drinking or using drugsNaltrexone should not be used to treat people who are still using street drugs or drinking large amounts of alcoholNaltrexone is in a class of medications called opiate antagonistsIt works by decreasing the craving for alcohol and blocking the effects of opiate medications and opioid street drugs.

If a more rapid transition from agonist to antagonist therapy is deemed necessary and appropriate by the healthcare providermonitor the patient closely in an appropriate medical setting where precipitated withdrawal can be managed.

The administration of REVIA is not associated with the development of tolerance or dependenceIn subjects physically dependent on opioidsREVIA will precipitate withdrawal symptomatology.

REVIA should be considered as only one of many factors determining the success of treatmentTo achieve the best possible treatment outcomeappropriate compliance-enhancing techniques should be implemented for all components of the treatment programincluding medication compliance.

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an in vitro cyp induction study demonstrated that naltrexone is not an inducer of cyp3a4 and cyp1a2.

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